Research papers on brain computer interfaces published today:
- by Mengfan LiA brain-computer interface (BCI) based on motor imagery (MI) provides additional control pathways by decoding the intentions of the brain. MI ability has great intra-individual variability, and the majority of MI-BCI systems are unable to adapt to this variability, leading to poor training effects. Therefore, prediction of MI ability is needed. In this study, we propose an MI ability predictor based on multi-frequency EEG features. To validate the performance of the predictor, a video-guided…
- by Yu QiHow the human motor cortex (MC) orchestrates sophisticated sequences of fine movements such as handwriting remains a puzzle. Here we investigate this question through Utah array recordings from human MC during attempted handwriting of Chinese characters (n = 306, each consisting of 6.3 ± 2.0 strokes). We find that MC activity evolves through a sequence of states corresponding to the writing of stroke fragments during complicated handwriting. The directional tuning curve of MC neurons remains…
- by Hanfei LiFlexible fibrous electrodes have emerged as a promising technology for implantable biosensing applications, offering significant advancements in the monitoring and manipulation of biological signals. This review systematically explores the key aspects of flexible fibrous electrodes, including the materials, structural designs, and fabrication methods. A detailed discussion of electrode performance metrics is provided, covering factors such as conductivity, stretchability, axial channel count,…
- by Zhenni YangThe human voltage-gated potassium channels KCNQ2, KCNQ3, and KCNQ5 can form homo- and heterotetrameric channels that are responsible for generating the neuronal M current and maintaining the membrane potential stable. Activation of KCNQ channels requires both the depolarization of membrane potential and phosphatidylinositol 4,5-bisphosphate (PIP(2)). Here, we report cryoelectron microscopy structures of the human KCNQ5-calmodulin (CaM) complex in the apo, PIP(2)-bound, and both PIP(2)- and the…
- by Miao TianCONCLUSION: Our findings reveal that the contralateral side contributes the most to motion trajectory regression than the ipsilateral side which improves the clarity and interpretability of the motion trajectory regression model. Specifically, the feature from channel C5 in the Mu band is crucial for the movement of the right hand, while the feature from channel C3 in the Beta band plays a vital role.
- by Simon KojimaOBJECTIVE: Recently, a novel language training using an auditory brain-computer interface (BCI) based on electroencephalogram recordings has been proposed for chronic stroke patients with aphasia. Tested with native German patients, it has shown significant and medium to large effect sizes in improving multiple aspects of language. During the training, the auditory BCI system delivers word stimuli using six spatially arranged loudspeakers. As delivering the word stimuli via headphones reduces…
- by Xiaonan GuoCONCLUSIONS: The findings highlighted an efficacy advantage with tolerated adverse event profiles for muscarinic receptor agonists in schizophrenia.
- by Yike SunBrain-computer interface (BCI) technology represents a burgeoning interdisciplinary domain that facilitates direct communication between individuals and external devices. The efficacy of BCI systems is largely contingent upon the progress in signal acquisition methodologies. This paper endeavors to provide an exhaustive synopsis of signal acquisition technologies within the realm of BCI by scrutinizing research publications from the last ten years. Our review synthesizes insights from both…
- by Zhikai YuTo derive critical signal features from intracranial electroencephalograms of epileptic patients in order to design instructions for feedback-type electrical stimulation systems. The Detrended Fluctuation Analysis (DFA) exponent is chosen as the classification exponent, and the disparities between indicators representing distinct seizure states and the classification efficacy of rudimentary machine learning models are computed. The DFA exponent exhibited a statistically significant variation…
- by Mengyue ZhuUnderstanding the anatomical connection and behaviors of transcriptomic neuron subtypes is critical to delineating cell type-specific functions in the brain. Here we integrated single-nucleus transcriptomic sequencing, in vivo circuit mapping, optogenetic and chemogenetic approaches to dissect the molecular identity and function of heterogeneous GABAergic neuron populations in the zona incerta (ZI) in mice, a region involved in modulating various behaviors. By microdissecting ZI for…
- by Hong YangBrain-computer interfaces (BCIs) have seen increasingly fast growth under the help from AI, algorithms, and cloud computing. While providing great benefits for both medical and educational purposes, BCIs involve processing of neural data which are uniquely sensitive due to their most intimate nature, posing unique risks and ethical concerns especially related to privacy and safe control of our neural data. In furtherance of human right protection such as mental privacy, data laws provide more…
- by Doris WangMovement decoding from invasive human recordings typically relies on a distributed system employing advanced machine learning algorithms programmed into an external computer for state classification. These brain-computer interfaces are limited to short-term studies in laboratory settings that may not reflect behavior and neural states in the real world. The development of implantable devices with sensing capabilities is revolutionizing the study and treatment of brain circuits. However, it is…
- by S HaroOBJECTIVE: There is significant research in accurately determining the focus of a listener's attention in a multi-talker environment using auditory attention decoding (AAD) algorithms. These algorithms rely on neural signals to identify the intended speaker, assuming that these signals consistently reflect the listener's focus. However, some listeners struggle with this competing talkers task, leading to suboptimal tracking of the desired speaker due to potential interference from distractors….
- by Bouke van BalenRecent developments in the domain of bi-directional Brain-Computer Interface (BCI) technology are directed at generating naturalistic sensory perceptual experiences for disabled people. I argue that conceptualizing and operationalizing "naturalness" in this context has profound impact on disabled people and their experiences. I ask (1) what does it mean to have a "natural" perceptual experience and (2) should the bi-directional BCI-community strive for naturalness in this context? Inspired by…
- by Chun-Ren PhangDeep reinforcement learning (RL) algorithms enable the development of fully autonomous agents that can interact with the environment. Brain-computer interface (BCI) systems decipher human implicit brain signals regardless of the explicit environment. We proposed a novel integration technique between deep RL and BCI to improve beneficial human interventions in autonomous systems and the performance in decoding brain activities by considering environmental factors. Shared autonomy was allowed…
- by Jianxiu LiElectroencephalography (EEG)-based motor imagery (MI) is extensively utilized in clinical rehabilitation and virtual reality-based movement control. Decoding EEG-based MI signals is challenging because of the inherent spatio-temporal variability of the original signal representation, coupled with a low signal-to-noise ratio (SNR), which impedes the extraction of clean and robust features. To address this issue, we propose a multi-scale spatio-temporal domain-invariant representation learning…
- by Andrea CalderoneBackground/Objectives: Guided imagery techniques, which include mentally picturing motions or activities to help motor recovery, are an important part of neuroplasticity-based motor therapy in stroke patients. Motor imagery (MI) is a kind of guided imagery in neurorehabilitation that focuses on mentally rehearsing certain motor actions in order to improve performance. This systematic review aims to evaluate the current evidence on guided imagery techniques and identify their therapeutic…
- by Jiaqi ZhengCONCLUSIONS: This study quantitatively evaluated the relationship between packet loss and neural decoding outcomes, highlighting the differential effects of loss patterns on decoding parameters, and it proposed some methods and devices to solve the problem of packet loss. These findings offer valuable insights for the development of resilient neural signal acquisition and processing systems capable of mitigating the impact of packet loss.
- by Seitaro IwamaMotor performance improvement through self-modulation of brain activity has been demonstrated through neurofeedback. However, the sensorimotor plasticity induced through the training remains unclear. Here, we combined individually tailored closed-loop neurofeedback, neurophysiology, and behavioral assessment to characterize how the training can modulate the somatosensory system and improve performance. The real-time neurofeedback of human electroencephalogram (EEG) signals enhanced participants'…
- by Jian LiuNeural recording and stimulation are fundamental techniques used for brain computer interfaces (BCIs). BCIs have significant potential for use in a range of brain disorders. However, for most BCIs, electrode implantation requires invasive craniotomy procedures, which have a risk of infection, hematoma, and immune responses. Such drawbacks may limit the extensive application of BCIs. There has been a rapid increase in the development of endovascular technologies and devices. Indeed, in a clinical…